# Do scripts support puzzles with more than 1 RNA sequance?

**URL:** https://forum.eternagame.org/t/do-scripts-support-puzzles-with-more-than-1-rna-sequance/2705
**Category:** Tools
**Created:** [June 19, 2016, 11:48am UTC](https://forum.eternagame.org/t/do-scripts-support-puzzles-with-more-than-1-rna-sequance/2705 "2016-06-19T11:48:00Z")
**Posts on this page:** 4
**Page:** 1

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### Author: ![atanas.atanasov](https://forum.eternagame.org/letter_avatar_proxy/v4/letter/a/47e85d/32.png) [@atanas.atanasov](https://forum.eternagame.org/u/atanas.atanasov)
#### Post date: [June 19, 2016, 11:48am UTC](https://forum.eternagame.org/t/do-scripts-support-puzzles-with-more-than-1-rna-sequance/2705/1 "2016-06-19T11:48:00Z")

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As far as I could see, the script library support calculating free energy given a fold and finding a the fold of the min free energy of an RNA sequence. The TB puzzles use more than 1 RNA sequence and I was wondering if the script can compute those and how to do that. The nupack server uses the a “+” to denote where another RNA sequence begins. I tried that but it doesn’t seem to work with the script library (I think it ignores everything different than a base letter).

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### Author: ![Omei](https://forum.eternagame.org/user_avatar/forum.eternagame.org/omei/32/4420_2.png) [@Omei](https://forum.eternagame.org/u/Omei)
#### Post date: [June 19, 2016, 8:32pm UTC](https://forum.eternagame.org/t/do-scripts-support-puzzles-with-more-than-1-rna-sequance/2705/2 "2016-06-19T20:32:00Z")

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I know the flash app uses & instead of +. &nbsp;But the library may not have been touched for years, before Eterna moved on to emphasizing switches.

You can do&nbsp;what I think you want eith&nbsp;LFP’s script&nbsp;[http://www.eternagame.org/web/script/7005225/](http://www.eternagame.org/web/script/7005225/ "Link http//wwweternagameorg/web/script/7005225/"). &nbsp; This is something he did as a critical part of getting predicted foldings into the new data browser’s database.

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### Author: ![atanas.atanasov](https://forum.eternagame.org/letter_avatar_proxy/v4/letter/a/47e85d/32.png) [@atanas.atanasov](https://forum.eternagame.org/u/atanas.atanasov)
#### Post date: [June 19, 2016, 9:53pm UTC](https://forum.eternagame.org/t/do-scripts-support-puzzles-with-more-than-1-rna-sequance/2705/3 "2016-06-19T21:53:00Z")

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Thanks, I’ll see what I can do with that. What about puzzle creator, is it possible to create custom puzzles that have more than 1 RNA?

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### Author: ![Omei](https://forum.eternagame.org/user_avatar/forum.eternagame.org/omei/32/4420_2.png) [@Omei](https://forum.eternagame.org/u/Omei)
#### Post date: [June 19, 2016, 11:23pm UTC](https://forum.eternagame.org/t/do-scripts-support-puzzles-with-more-than-1-rna-sequance/2705/4 "2016-06-19T23:23:00Z")

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No, puzzle creator is limited to FMN and MS2 ligands. &nbsp;(That’s all Eterna had until recently, and the puzzle creator hasn’t been updated.)
