# \[Market strategy\] GU's in long stems

**URL:** https://forum.eternagame.org/t/market-strategy-gus-in-long-stems/1997
**Category:** Strategy Market - Single State
**Created:** [December 1, 2013, 11:39am UTC](https://forum.eternagame.org/t/market-strategy-gus-in-long-stems/1997 "2013-12-01T11:39:00Z")
**Posts on this page:** 3
**Page:** 1

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### Author: ![Eli\_Fisker](https://forum.eternagame.org/user_avatar/forum.eternagame.org/eli_fisker/32/4453_2.png) [@Eli\_Fisker](https://forum.eternagame.org/u/Eli_Fisker)
#### Post date: [December 1, 2013, 11:39am UTC](https://forum.eternagame.org/t/market-strategy-gus-in-long-stems/1997/1 "2013-12-01T11:39:00Z")

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Give +1 if a stem at the length of 8+ contains a GU-basepair at least 2 basepairs away from the closing basepairs.

For every additional +7 basepairs a stem is long give +1 if there is another GU basepair.

Background: [https://getsatisfaction.com/eternagam…](https://getsatisfaction.com/eternagame/topics/designs_that_crave_gu)

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### Author: ![eternacac](https://forum.eternagame.org/letter_avatar_proxy/v4/letter/e/977dab/32.png) [@eternacac](https://forum.eternagame.org/u/eternacac)
#### Post date: [December 3, 2013, 9:35am UTC](https://forum.eternagame.org/t/market-strategy-gus-in-long-stems/1997/2 "2013-12-03T09:35:00Z")

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If you will remember I have posted a graph/chart from a paper somewhere that shows GU’s approximately every 4th base pair helps natural RNA, so this makes great sense to me.

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### Author: ![Eli\_Fisker](https://forum.eternagame.org/user_avatar/forum.eternagame.org/eli_fisker/32/4453_2.png) [@Eli\_Fisker](https://forum.eternagame.org/u/Eli_Fisker)
#### Post date: [December 3, 2013, 11:46am UTC](https://forum.eternagame.org/t/market-strategy-gus-in-long-stems/1997/4 "2013-12-03T11:46:00Z")

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Hi Chris! I didn’t remember but thx for reminding me! Nice knowing that I’m in agreement with scientists too. I also think that GU’s will be accepted in a much higher rate than I say in my strategy, as I see this ín some designs. But I started out safely on a tendency on where I think they will be most urgently needed. I also see the same tendency for usefulness of non canonical basepairs just like the GU’s, in Rfam and for Brourd’s ingame experiments too.
