# Need Advice on RNA Folding Algorithms

**URL:** https://forum.eternagame.org/t/need-advice-on-rna-folding-algorithms/4910
**Category:** General Science Discussion
**Created:** [April 23, 2024, 3:52am UTC](https://forum.eternagame.org/t/need-advice-on-rna-folding-algorithms/4910 "2024-04-23T03:52:26Z")
**Posts on this page:** 3
**Page:** 1

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### Author: ![elija6266](https://forum.eternagame.org/user_avatar/forum.eternagame.org/elija6266/32/7022_2.png) [@elija6266](https://forum.eternagame.org/u/elija6266)
#### Post date: [April 23, 2024, 3:52am UTC](https://forum.eternagame.org/t/need-advice-on-rna-folding-algorithms/4910/1 "2024-04-23T03:52:26Z")

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Hello there,

I am working on a project that involves RNA folding algorithms; and I am seeking advice from those experienced in this area. Specifically, I am interested in understanding the strengths and limitations of different algorithms used for predicting RNA secondary structures.

Could you please share your insights on the following questions;

What are the most commonly used algorithms for RNA folding prediction?  
How do these algorithms compare in terms of accuracy and efficiency?  
Are there any recent advancements in RNA folding algorithms that I should be aware of?  
Are there any specific tools or software packages that you recommend for RNA folding prediction?  
How do you validate the predictions made by these algorithms in your research or projects?

Also, I have gone through this; [https://forum.eternagame.org/t/folding-algorithm/2260](https://forum.eternagame.org/t/folding-algorithm/2260)[blue](https://www.igmguru.com/machine-learning-ai/blue-prism-training/) which definitely helped me out a lot.

Any additional resources, tips, or advice on working with RNA folding algorithms would be greatly appreciated.

Thank you in advance for your help and assistance.

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### Author: ![TeachDNAdotNET](https://forum.eternagame.org/letter_avatar_proxy/v4/letter/t/48db29/32.png) [@TeachDNAdotNET](https://forum.eternagame.org/u/TeachDNAdotNET)
#### Post date: [April 25, 2024, 10:40pm UTC](https://forum.eternagame.org/t/need-advice-on-rna-folding-algorithms/4910/2 "2024-04-25T22:40:32Z")

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Check out RNA Central - I think they are on the cutting edge, and offer free tools.

> **[RNAcentral: The non-coding RNA sequence database](https://rnacentral.org/)**
>
> RNAcentral is a comprehensive database of non-coding RNA sequences

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### Author: ![JR1](https://forum.eternagame.org/letter_avatar_proxy/v4/letter/j/dfb087/32.png) [@JR1](https://forum.eternagame.org/u/JR1)
#### Post date: [April 26, 2024, 4:38pm UTC](https://forum.eternagame.org/t/need-advice-on-rna-folding-algorithms/4910/3 "2024-04-26T16:38:42Z")

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Go to this lab: [Eterna](https://eternagame.org/labs/11311397) and down scroll through the conclusions and you will find a list of folding algorithms compared to one another and several charts.