# \[Strategy Market\] G and C bases in GC pairs

**URL:** https://forum.eternagame.org/t/strategy-market-g-and-c-bases-in-gc-pairs/1396
**Category:** Strategy Market - Single State
**Created:** [August 13, 2012, 9:59pm UTC](https://forum.eternagame.org/t/strategy-market-g-and-c-bases-in-gc-pairs/1396 "2012-08-13T21:59:00Z")
**Posts on this page:** 3
**Page:** 1

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### Author: ![Dr\_Drax](https://forum.eternagame.org/letter_avatar_proxy/v4/letter/d/bb73d2/32.png) [@Dr\_Drax](https://forum.eternagame.org/u/Dr_Drax)
#### Post date: [August 13, 2012, 9:59pm UTC](https://forum.eternagame.org/t/strategy-market-g-and-c-bases-in-gc-pairs/1396/1 "2012-08-13T21:59:00Z")

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I’d like to submit a strategy:

Rank designs based on the percentage of G and C bases that are part of GC pairs as a fraction of total G and C pairs.

That is: score = (200 \* number of GC pairs) / (total G bases + total C bases)

So a design where all Gs and Cs are part of GC pairs would score 100, and a design where all Gs and Cs were either unpaired or part of GU pairs would score 0.

If possible, I’d like to exclude from the calculation G and C bases that are locked, such as in aptamer rings that are fixed for a given lab.

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### Author: ![jandersonlee](https://forum.eternagame.org/letter_avatar_proxy/v4/letter/j/a9a28c/32.png) [@jandersonlee](https://forum.eternagame.org/u/jandersonlee)
#### Post date: [August 14, 2012, 9:19pm UTC](https://forum.eternagame.org/t/strategy-market-g-and-c-bases-in-gc-pairs/1396/2 "2012-08-14T21:19:00Z")

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Slight nit: what if there are no Gs or Cs? Divide by zero error, but should probably score as 0 (cub scout design).

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### Author: ![Dr\_Drax](https://forum.eternagame.org/letter_avatar_proxy/v4/letter/d/bb73d2/32.png) [@Dr\_Drax](https://forum.eternagame.org/u/Dr_Drax)
#### Post date: [August 14, 2012, 10:29pm UTC](https://forum.eternagame.org/t/strategy-market-g-and-c-bases-in-gc-pairs/1396/3 "2012-08-14T22:29:00Z")

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You’re right - that is a possibility. Since cub scout designs are known to do badly in synthesis, I agree with your suggestion that such designs should score 0 rather than crash the scoring algorithm.

I would hope all of the strategy market algorithms are implemented with exception handling, but I don’t know if that’s actually the case. Thanks for pointing out my oversight.
