Hi everybody,
I read a lot of thing about this level, I’ve tried for along time, but I can’t do it !
Is anybody can help me ?
Thanks
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One of the comments says to place a C at the main RNA sequence # 66. If you do that, look for a base in the TB-A oligo that would match this “C” base. There are two. #66-C will bind with TB-A # 106 or 100. Both are G’s. Continue to select bases from 67 and up to compliment the TB-A oligo. It will take several bases to make a strong enough attraction to pull in TB-A. When it does, see what happens to the MS2 hairpin. You need a series of bases that will break the MS2 hairpin. ( Hint: one will and one won’t).
This is not a solution it is a start of a solution